The long-awaited, longer-lasting neuromodulator drug DaxibotulinumtoxinA for injection (DAXI), a botulinum toxin type A formulated with a novel peptide excipient may be nearing US FDA approval. The studies have shown that DAXI is effective for treating neck spasms (cervical dystonia) and for reducing the appearance of frown lines. While this one is hardly as life-changing, for those of us who use Botox and its counterparts for reducing wrinkles, restraining overactive muscle movement, or controlling sweats, this is pretty exciting.
How long will it last?
When will you see the results?
Is Daxi safe?
Daxi is considered to be very safe. Daxi may be safer than other Botox-like products according to the American Board of Cosmetic Surgery for a few reasons:
Unlike Botox, Daxi is stable at room temperature and doesn't require refrigeration.
Daxi doesn't contain albumin, a blood-derived protein used in other botulinum toxin brands as a stabilizer to protect the neurotoxin complex during manufacturing, shipping, storage, and administration. Albumin carries a very remote risk of viral disease transmission.
Potential Side Effects
The side effects seen with DAXI are consistent in nature and frequency with those seen with other botulinum toxin products. If it is injected in the wrong area, there is a risk of ending up with a drooping eyelid or eyebrow, so it’s important to go to a practitioner who is licensed in administering neurotoxins to ensure correct placement.
If you’re familiar with Botox and its counterparts, but often wish you could stretch the time between treatments, DAXI might be a very promising option for you. Also, people with a busy lifestyle who doesn't have time to come in to be treated three to four times a year would be a great candidate for DAXI.